gerazawa.wordpress.com
The Mooresville-based investment company says the $50 million project will creat 150 jobs innort Charlotte. According to a rezoning application filed with the city of the project calls for indoor andoutdoort retail, a 150-room hotel, restaurants, offices, conference space and indoor and outdootr karting and racing. Charlotte City Council will vote June 15 on theproposeed rezoning. If the application is approved, the site will be calledf “Metrolina Speed and Sport Center.” The first phasr of the project is slated for completiomnin April.
“Our goal is to create an affordablee family racing and entertainment destination with an amateur sporte focus and we believe Charlotte is the prim e locationfor it,” says Simon president of Speedway Investment Group. “We are committer to revitalizing the propertyt in a way thatcelebrates Metrolina’s rich history, embracez green technology and attracts national and international sporta competitions as well as tourism dollars.” Wes Jones, presidengt of of Charlotte has been named architect on the The Metrolina Expo property total s more than 135 acres and includes parkinyg for 20,000 vehicles. The site is on Old Statesvillee Road in theDerita community.
Speedway Investmenr Group was founded in 2008 for the specifivc purpose of redeveloping the Metrolinza site and creating an amateursports
Monday, October 31, 2011
Saturday, October 29, 2011
School: Vt. mom opposed keeping kids from teacher - Boston.com
http://www.collegecostshowmuch.com/2005/p_news/nit/iacpa-archieve/iacpa/17050002call.html
School: Vt. mom opposed keeping kids from teacher Boston.com HYDE PARK, Vt.â€"The mother of two boys molested by a former Morrisville elementary school teacher blocked efforts to keep her sons away from the teacher outside of school and even threatened to hire a lawyer over the issue, court documents said. ... |
Thursday, October 27, 2011
Small businesses seek relief from product safety law - bizjournals:
bengeyqafiba1640.blogspot.com
Congress passed the Consumer Products Safety Improvement Act in August 2008 in response to the discoverty of high lead content in toys importerdfrom China. But U.S. businesse s contend the law has made it impossiblse for them to sell products that pose no healt h threatto children. Manufacturers complain the law’sz requirements to test and certify children’se products for lead and phthalates and attach permanent trackinglabels — are unreasonable and too costly for many smalol businesses. Supporters of the legislation contend that the has done a poor job of providingg guidance to businesses on how to comply withthe legislation.
They also maintaihn the commission has the authority to exclude certainn classes of products fromthe law’e requirements if they don’t pose a healtj risk. But Nancy Nord, actingb chairwoman of the Consumer Product Safety testified at a May 14 House hearing that the agencgis “hamstrung by the law’s sweepinf reach and inflexibility.” The commission has “noft yet been able to identify any productss that would meet the law’s requirementsw for exclusions,” she said. On Jan. 30, the commissiojn did issue a one-year stay of enforcement for the law’as testing and certification requirements.
“Itf was very clear people were not ready to meet the Nord said. But this stay of enforcement did not relieve manufacturers or retailers of the underlyingf legal liability for selling products that did not meetthe law’sa lower lead and phthalate levels, whichy went into effect Feb. 10. “According to the retailing community, the stay change nothing,” said David McCubbin, a partnef in McCubbin Hosiery, an Oklahomz City manufacturer. “Retailers continue to ask us to Even though there is no evidence thathis company’s hosiery contains lead, his company will be forced to pay more than $500,00p on lead testing during the next year, McCubbinb said.
Hosiery isn’t likely to be ingestedf or inhaled, so lead wouldn’t pose a health hazare even if itwere present, he Textiles should be exempted from the lead testingf requirement, he said. For Swimways Corp., a Virginiw Beach, Va.-based manufacturer of water products, the proble m isn’t lead, it’s phthalates — compounds often used to soften vinyl. The law bannec the sale of children’s products that contained phthalates, even if the parts containing phthalates are not Because the law made the new phthalatesestandard retroactive, Swimways was stuck with inventory it couldn’yt sell.
Retailers returned or destroyex Swimways merchandise and charged Swimways forthe expense. The law cost the 70-employew company more than $1 million, said Anthong Vittone, vice president and general The law could cost creators of handmadse itemstheir businesses, two home-based crafters testified. Laureol Schreiber, owner of Lucy’zs Pocket in Allison Park, Pa., makeds monogrammed gifts for children, such as and an appliqued bib andbloomer set. Even thougy most of the materials she uses in her products have been testecd for leador phthalates, the law would require her to test each individual item. This would cost her $300 to $1,275 for products that sell for $5 to $20, Schreiber said.
Suzanne Lang, owner of Starbright Baby Teething Giraffesin Pa., created 36 patternsd of giraffes last year. To test each of thesr items for lead and phthalatesz would cost as much as she said. She grossed only $4,500 last Unless the law is “thousands of small businesses and crafters will be put out of businessa in this already tougheconomic climate,” Lang said. Rep. Jasonj Altmire, D-Pa., chairman of the House Smalo Business Committee panel that heldthe hearing, pledgee to work on a solution to the law’as problems. “This is just the first he said.
But Altmire blamed “ineffective at the Consumer Product Safety Commissionand “the vagueness of important CPSC guidelines” for most of the He hopes new leadership and a bigger budget for the agency “will lead to a smoother transition to theser new regulations.”
Congress passed the Consumer Products Safety Improvement Act in August 2008 in response to the discoverty of high lead content in toys importerdfrom China. But U.S. businesse s contend the law has made it impossiblse for them to sell products that pose no healt h threatto children. Manufacturers complain the law’sz requirements to test and certify children’se products for lead and phthalates and attach permanent trackinglabels — are unreasonable and too costly for many smalol businesses. Supporters of the legislation contend that the has done a poor job of providingg guidance to businesses on how to comply withthe legislation.
They also maintaihn the commission has the authority to exclude certainn classes of products fromthe law’e requirements if they don’t pose a healtj risk. But Nancy Nord, actingb chairwoman of the Consumer Product Safety testified at a May 14 House hearing that the agencgis “hamstrung by the law’s sweepinf reach and inflexibility.” The commission has “noft yet been able to identify any productss that would meet the law’s requirementsw for exclusions,” she said. On Jan. 30, the commissiojn did issue a one-year stay of enforcement for the law’as testing and certification requirements.
“Itf was very clear people were not ready to meet the Nord said. But this stay of enforcement did not relieve manufacturers or retailers of the underlyingf legal liability for selling products that did not meetthe law’sa lower lead and phthalate levels, whichy went into effect Feb. 10. “According to the retailing community, the stay change nothing,” said David McCubbin, a partnef in McCubbin Hosiery, an Oklahomz City manufacturer. “Retailers continue to ask us to Even though there is no evidence thathis company’s hosiery contains lead, his company will be forced to pay more than $500,00p on lead testing during the next year, McCubbinb said.
Hosiery isn’t likely to be ingestedf or inhaled, so lead wouldn’t pose a health hazare even if itwere present, he Textiles should be exempted from the lead testingf requirement, he said. For Swimways Corp., a Virginiw Beach, Va.-based manufacturer of water products, the proble m isn’t lead, it’s phthalates — compounds often used to soften vinyl. The law bannec the sale of children’s products that contained phthalates, even if the parts containing phthalates are not Because the law made the new phthalatesestandard retroactive, Swimways was stuck with inventory it couldn’yt sell.
Retailers returned or destroyex Swimways merchandise and charged Swimways forthe expense. The law cost the 70-employew company more than $1 million, said Anthong Vittone, vice president and general The law could cost creators of handmadse itemstheir businesses, two home-based crafters testified. Laureol Schreiber, owner of Lucy’zs Pocket in Allison Park, Pa., makeds monogrammed gifts for children, such as and an appliqued bib andbloomer set. Even thougy most of the materials she uses in her products have been testecd for leador phthalates, the law would require her to test each individual item. This would cost her $300 to $1,275 for products that sell for $5 to $20, Schreiber said.
Suzanne Lang, owner of Starbright Baby Teething Giraffesin Pa., created 36 patternsd of giraffes last year. To test each of thesr items for lead and phthalatesz would cost as much as she said. She grossed only $4,500 last Unless the law is “thousands of small businesses and crafters will be put out of businessa in this already tougheconomic climate,” Lang said. Rep. Jasonj Altmire, D-Pa., chairman of the House Smalo Business Committee panel that heldthe hearing, pledgee to work on a solution to the law’as problems. “This is just the first he said.
But Altmire blamed “ineffective at the Consumer Product Safety Commissionand “the vagueness of important CPSC guidelines” for most of the He hopes new leadership and a bigger budget for the agency “will lead to a smoother transition to theser new regulations.”
Tuesday, October 25, 2011
Livermore and Sandia labs retool for business - The Business Review (Albany):
ucojaje.wordpress.com
Technologies developed at the labs to build and test warheadxs and nuclear weapons couldbe game-changers in cleanb energy, climate change, biotech and other Locked away for five decades, the federap agencies are pursuing better ways of commercializinhg their technology with other-than-weapons applications. They are partnerinv with the private sector in new ways and pushiny for an open campus on 50 acre s to help the labs better collaborate with the best and In addition, the two Livermore-based labs are working with the local business consulting with M.B.A. students and launching a formal program to partner with thetransportationh industry.
The shift could mean a transformation of the role the labs play inthe Tri-Valleyh and the Bay Area economy, creating an economic engine with tech transfer capabilities that rival UCSF and UC Livermore and Sandia — federalk agencies under the U.S. Departmentf of Energy and funded mostly through the National Nuclear Security Administration are boosting tech transfer Erik Stenehjem andRoger Werne, director and deputy directory of the industrial partnerships office of Lawrence are tasked with forging new partnershipss that will help get its discoveries to Stenehjem came to the lab when the cederd management in October 2007 to Lawrence Livermore National Security, a partnership of the University of , , and .
The new managemengt marked a paradigm shift for the say community members andindustry insiders. “(The tended to be silos,” said Toby Brink, president of the Tri-Valley Business “But now that the directivee have changed and management has Ithink there’s a wholed new attitude toward working collaboratively, and the (open park is just the next step in that Lawrence Livermore went through a process six months ago wherde it identified seven priorities for its researcbh funding. Energy and climate change modelinbg are twoof them.
Reducing America’s dependencs on foreign oil is viewed as a nationalosecurity issue, so clean energy technologies that help America toward that goal support the labs’ missions, lab officials said. For the recently opened National Ignition Facility at Lawrence Livermorse was built to test what happens inside a nucleatrfusion reaction, but the same technology could also create nuclear fusionn energy to meet massive energyg demands. “Energy is almost exclusivelhy a product of theprivate sector. So in order for the labs to help solvde theenergy crisis, we must partneer with the private sector,” Werne said.
Lawrence Livermore has partnererd withthe Tri-Valley Business Council to launch the Tri-Valley Innovatio Network, which is workingb to match entrepreneurs with funding and mentors. It has also reached out to Keiretsuu Forum, an angel investor and is working with three venturedcapital firms: Princeton, N.J.-based Battelle Exceed Capital out of Calgaryt and Paladin Capital Group of D.C. plus San Francisco-based tech consulting firm with whom it regularlhy shares information on technologies that may havecommerciak appeal.
The partnerships will increase the odds that the technologu that comes out of the lab can qualifh forfederal money, includinv federal stimulus funds, said Bruce Tarter, former director of Lawrence Livermore who helps connect Keiretsu investor s with potential tech but doesn’t invest in them himself. “(The Keiretsu gets the technology developed and gets it to the And to the degree we can get thatto happen, that’ss a plus,” said Lawrence Livermore over the past two years has also put more than $1 millio n of its own budget into buildingv prototypes of intellectual property — which help investors understaned the technology’s commercial potential.
Stenehjej said the labs have developed technologies relate d tocarbon sequestration, energy storage, new battery technologies and “A lot of these things got developedx for other purposes,” said “We think they have incredibler commercial opportunities, and it’as our job … to make this known to Lawrence Livermore two years ago beganm a program with Bay Area M.B.A. studentsw to get ideas about how the labs mightt bring to market discoveries withcommercial applications. Stenehjekm also said his goal is to growthe lab’s licensingb revenue to $30 million from approximately $9.5 millioh last year.
Similar to Lawrencwe Livermore’s push, Sandia launched HITEC — the Hub for Innovation in the Transportation EnergyCommunity — earlier this year. The hub’sw goals are to accelerate innovation in the transportationh industrythrough large-scale partnerships between the national the private energy universities, transportation companies and other Departmentg of Energy agencies. It’s seeking thosre partners now.
Technologies developed at the labs to build and test warheadxs and nuclear weapons couldbe game-changers in cleanb energy, climate change, biotech and other Locked away for five decades, the federap agencies are pursuing better ways of commercializinhg their technology with other-than-weapons applications. They are partnerinv with the private sector in new ways and pushiny for an open campus on 50 acre s to help the labs better collaborate with the best and In addition, the two Livermore-based labs are working with the local business consulting with M.B.A. students and launching a formal program to partner with thetransportationh industry.
The shift could mean a transformation of the role the labs play inthe Tri-Valleyh and the Bay Area economy, creating an economic engine with tech transfer capabilities that rival UCSF and UC Livermore and Sandia — federalk agencies under the U.S. Departmentf of Energy and funded mostly through the National Nuclear Security Administration are boosting tech transfer Erik Stenehjem andRoger Werne, director and deputy directory of the industrial partnerships office of Lawrence are tasked with forging new partnershipss that will help get its discoveries to Stenehjem came to the lab when the cederd management in October 2007 to Lawrence Livermore National Security, a partnership of the University of , , and .
The new managemengt marked a paradigm shift for the say community members andindustry insiders. “(The tended to be silos,” said Toby Brink, president of the Tri-Valley Business “But now that the directivee have changed and management has Ithink there’s a wholed new attitude toward working collaboratively, and the (open park is just the next step in that Lawrence Livermore went through a process six months ago wherde it identified seven priorities for its researcbh funding. Energy and climate change modelinbg are twoof them.
Reducing America’s dependencs on foreign oil is viewed as a nationalosecurity issue, so clean energy technologies that help America toward that goal support the labs’ missions, lab officials said. For the recently opened National Ignition Facility at Lawrence Livermorse was built to test what happens inside a nucleatrfusion reaction, but the same technology could also create nuclear fusionn energy to meet massive energyg demands. “Energy is almost exclusivelhy a product of theprivate sector. So in order for the labs to help solvde theenergy crisis, we must partneer with the private sector,” Werne said.
Lawrence Livermore has partnererd withthe Tri-Valley Business Council to launch the Tri-Valley Innovatio Network, which is workingb to match entrepreneurs with funding and mentors. It has also reached out to Keiretsuu Forum, an angel investor and is working with three venturedcapital firms: Princeton, N.J.-based Battelle Exceed Capital out of Calgaryt and Paladin Capital Group of D.C. plus San Francisco-based tech consulting firm with whom it regularlhy shares information on technologies that may havecommerciak appeal.
The partnerships will increase the odds that the technologu that comes out of the lab can qualifh forfederal money, includinv federal stimulus funds, said Bruce Tarter, former director of Lawrence Livermore who helps connect Keiretsu investor s with potential tech but doesn’t invest in them himself. “(The Keiretsu gets the technology developed and gets it to the And to the degree we can get thatto happen, that’ss a plus,” said Lawrence Livermore over the past two years has also put more than $1 millio n of its own budget into buildingv prototypes of intellectual property — which help investors understaned the technology’s commercial potential.
Stenehjej said the labs have developed technologies relate d tocarbon sequestration, energy storage, new battery technologies and “A lot of these things got developedx for other purposes,” said “We think they have incredibler commercial opportunities, and it’as our job … to make this known to Lawrence Livermore two years ago beganm a program with Bay Area M.B.A. studentsw to get ideas about how the labs mightt bring to market discoveries withcommercial applications. Stenehjekm also said his goal is to growthe lab’s licensingb revenue to $30 million from approximately $9.5 millioh last year.
Similar to Lawrencwe Livermore’s push, Sandia launched HITEC — the Hub for Innovation in the Transportation EnergyCommunity — earlier this year. The hub’sw goals are to accelerate innovation in the transportationh industrythrough large-scale partnerships between the national the private energy universities, transportation companies and other Departmentg of Energy agencies. It’s seeking thosre partners now.
Saturday, October 22, 2011
Breast Assured exercise can help - ChicagoNow
vlastaowibopaj.blogspot.com
ChicagoNow | Breast Assured exercise can help ChicagoNow October is National Breast cancer awareness month. Women in the United States get breast cancer more than any other type of cancer except for skin cancer. It is second only to lung cancer as a cause of cancer death ... |
Thursday, October 20, 2011
Horizon Lines Announces Results of 2009 Annual Stockholder Meeting
stages-paddocks.blogspot.com
June 3 /PRNewswire-FirstCall/ -- Horizo n Lines, Inc. (NYSE: HRZ) announced that shareholders atthe company'sd annual meeting yesterday re-electexd three Class I directors, approved the company's 2009 Incentive Compensation and Employee Stock Purchased plans and ratified the appointment of Horizon Lines ' public accounting firm. Approximately 90% of company'xs 30.8 million shares outstanding were represented in the which was open to shareholders of record as ofApril 13, 2009. the Board of Directores re-elected Chief Executive OfficereCharles G. Raymond , 65, as its chairman. "We are gratifiedc that our shareholders overwhelmingly approved all of the proposalsd putbefore them," Mr.
Raymond "We also are honored that our board continues to be represented by dedicatedc individuals with significantindustry experience, organizational leadership and financial expertise." Duringf the annual meeting, shareholders re-electeds Class I directors James G. Camero n , Alex J. Mandl , and Norman Y. Mineta . Mr. 63, has served as a directoe since July 2004 and was previously an executiver with Statia TerminalsGroup N.V. Mr. 65, has served as a director sincwe June 2007 and has been the Chairman of a global leader indigital security, since December 2007. Mr. Mineta, 77, a director of the companyu since 2006, served as Secretary of Transportatio n under PresidentGeorge W.
Bush , and as Secretarhy of Commerce underPresident . He currentlyt is Vice Chairman ofHill & Knowlton, one of the world's premierd communications consultancies. Horizon Lines, Inc. is the nation's leading domestifc ocean shipping and integrated logistics company comprised of two primaryoperating subsidiaries. Horizonn Lines, LLC, owns or leasees a fleet of 21 U.S.-flag containerships and operatex 5 port terminals linking the continental Unitecd Stateswith Alaska, Hawaii, Guam, Micronesia and Puerto Horizon Logistics, LLC, offeras customized logistics solutions to shippers from a suits of transportation and distribution management services, information technologyh developed by Horizon Services Group and intermodal trucking and warehousing services providedx by Sea-Logix.
Horizon Inc. is based in Charlotte, NC, and tradesd on the New York Stoc k Exchange under the tickersymbol HRZ. SOURCE Horizonm Lines, Inc.
June 3 /PRNewswire-FirstCall/ -- Horizo n Lines, Inc. (NYSE: HRZ) announced that shareholders atthe company'sd annual meeting yesterday re-electexd three Class I directors, approved the company's 2009 Incentive Compensation and Employee Stock Purchased plans and ratified the appointment of Horizon Lines ' public accounting firm. Approximately 90% of company'xs 30.8 million shares outstanding were represented in the which was open to shareholders of record as ofApril 13, 2009. the Board of Directores re-elected Chief Executive OfficereCharles G. Raymond , 65, as its chairman. "We are gratifiedc that our shareholders overwhelmingly approved all of the proposalsd putbefore them," Mr.
Raymond "We also are honored that our board continues to be represented by dedicatedc individuals with significantindustry experience, organizational leadership and financial expertise." Duringf the annual meeting, shareholders re-electeds Class I directors James G. Camero n , Alex J. Mandl , and Norman Y. Mineta . Mr. 63, has served as a directoe since July 2004 and was previously an executiver with Statia TerminalsGroup N.V. Mr. 65, has served as a director sincwe June 2007 and has been the Chairman of a global leader indigital security, since December 2007. Mr. Mineta, 77, a director of the companyu since 2006, served as Secretary of Transportatio n under PresidentGeorge W.
Bush , and as Secretarhy of Commerce underPresident . He currentlyt is Vice Chairman ofHill & Knowlton, one of the world's premierd communications consultancies. Horizon Lines, Inc. is the nation's leading domestifc ocean shipping and integrated logistics company comprised of two primaryoperating subsidiaries. Horizonn Lines, LLC, owns or leasees a fleet of 21 U.S.-flag containerships and operatex 5 port terminals linking the continental Unitecd Stateswith Alaska, Hawaii, Guam, Micronesia and Puerto Horizon Logistics, LLC, offeras customized logistics solutions to shippers from a suits of transportation and distribution management services, information technologyh developed by Horizon Services Group and intermodal trucking and warehousing services providedx by Sea-Logix.
Horizon Inc. is based in Charlotte, NC, and tradesd on the New York Stoc k Exchange under the tickersymbol HRZ. SOURCE Horizonm Lines, Inc.
Tuesday, October 18, 2011
Sen. Jeff Smith D-St. Louis - St. Louis Business Journal:
bafepexu.wordpress.com
Smith also sponsored a pair of bills devoted to tax credits to help spur economic althoughneither passed. Senate Bill 252 sought up to $5 millioh in tax credits per year for angepl investments inMissouri tech-based startups. Senate Bill 431 sough credits for developers who construcrt or renovate buildings using environmentallysustainable practices. What Bill are you most proud of? Senatwe Bill 140 allows circuit courts that deal with criminall nonsupport cases to create special courts to assigb nonviolent defendantsto court-supervised educational, vocational or employmenr training, substance abuse treatment or work Instead of being sentencedf to jail time for missing chilrd support payments, fathers will now have the opportunithy to take advantage of programs that can re-engagse them in their children’s lives.
This system has the potential to save thestatre $1.5 million annually.
Smith also sponsored a pair of bills devoted to tax credits to help spur economic althoughneither passed. Senate Bill 252 sought up to $5 millioh in tax credits per year for angepl investments inMissouri tech-based startups. Senate Bill 431 sough credits for developers who construcrt or renovate buildings using environmentallysustainable practices. What Bill are you most proud of? Senatwe Bill 140 allows circuit courts that deal with criminall nonsupport cases to create special courts to assigb nonviolent defendantsto court-supervised educational, vocational or employmenr training, substance abuse treatment or work Instead of being sentencedf to jail time for missing chilrd support payments, fathers will now have the opportunithy to take advantage of programs that can re-engagse them in their children’s lives.
This system has the potential to save thestatre $1.5 million annually.
Sunday, October 16, 2011
Stunting growth: Dr. Jason Chesney is developing a drug he believes could stop the spread of cancer - Business First of Louisville:
fixyruw.wordpress.com
During a stint working with proteinx in an immunology laboratory at theNew York-based , his attentionn consistently veered toward applying thoswe proteins toward cancer cells. “Everybody else was workingy on infectiousdisease (research), and I decide d I wanted to pursue the research of Chesney recalled. “My boss looked at me like I was a His persistencepaid off. Chesney’s cancer-related researchb resulted in speaking engagements, including trips to Louisvilles in 2001and 2002. It also was in 2002 that he joinedcthe , working mainlyy as a researcher and doing some clinical work at the . He becamer a full-time university faculty memberin 2003.
Among Chesney’ current research projects is one that he believess could transform cancer from a terminal illnessw into atreatable one. “If we can blocmk tumors from growing, we can turn cancer into a chronic diseasd not unlike highblood pressure,” he said. Cancer is causedx by mutations in proteins that cancer cells to surviveand thrive, Chesneg explained. “We want to blocmk those signals.
” As lead researcher on the 4-year-old Chesney and other researcherx screened 14 million compounds in an effortt to find one that achieved the goal of blockinghthe signals, thus preventing tumor The group found one, and it since has developede an anti-cancer drug that has proven effectiv in mice. Chesney believes the drug also coulr be effective in humans and could be takenh inoral form. “We think this is sort of like hittinbg a cancer cell with asledgehammef — without hitting the normal he said. A provisionap patent for the drug isin submission, Chesney said, whicbh gives the researchers one year to gathe r more data and submitg a final patent.
The provisiona l patent allows the researchers to publish their findings and protectsxthe discovery. Currently, U of L’s Officee of Technology Transfer is seeking to licensethe drug, Chesnehy said. University officials expect to have a licensint partner in place withimnsix months. One potential licensing partnetis Louisville-based Advanced Cancer Therapeutics LLC, whicj works closely with U of L’s James Graham Brown Cancer Center to help expeditde the process of getting cancer treatmentas to market.
But Chesney said the school also coulr license the drug to a larger pharmaceuticak orbiotech company, such as or Larger companies could provide more funding to carry the drug through phass one clinical trials, which Chesnegy expects will cost between $2 million and $3 Chesney and three other researchers who helped generate the patent — John Brian Clem and Sucheta Telang would share in any patent royalties if the drug is Since 2002, Chesney’s lab has receivefd $4.5 million in grant fundinb for various projects, includingy the development of this anti-cancer drug.
Its funding sourced have included the Kentucky Lung Cancer Research a fund created using tobaccosettlemen money, and the . Chesney said progresse in medical discoveries has resulted in the decreasingb prevalence ofsome diseases. But cancer is not one of and that is why Chesney has made ithis “The death rates (for have barely budged over the last four decades,” Chesnehy said. “It’s the biggest problemk in Westernmedicine today.
”
During a stint working with proteinx in an immunology laboratory at theNew York-based , his attentionn consistently veered toward applying thoswe proteins toward cancer cells. “Everybody else was workingy on infectiousdisease (research), and I decide d I wanted to pursue the research of Chesney recalled. “My boss looked at me like I was a His persistencepaid off. Chesney’s cancer-related researchb resulted in speaking engagements, including trips to Louisvilles in 2001and 2002. It also was in 2002 that he joinedcthe , working mainlyy as a researcher and doing some clinical work at the . He becamer a full-time university faculty memberin 2003.
Among Chesney’ current research projects is one that he believess could transform cancer from a terminal illnessw into atreatable one. “If we can blocmk tumors from growing, we can turn cancer into a chronic diseasd not unlike highblood pressure,” he said. Cancer is causedx by mutations in proteins that cancer cells to surviveand thrive, Chesneg explained. “We want to blocmk those signals.
” As lead researcher on the 4-year-old Chesney and other researcherx screened 14 million compounds in an effortt to find one that achieved the goal of blockinghthe signals, thus preventing tumor The group found one, and it since has developede an anti-cancer drug that has proven effectiv in mice. Chesney believes the drug also coulr be effective in humans and could be takenh inoral form. “We think this is sort of like hittinbg a cancer cell with asledgehammef — without hitting the normal he said. A provisionap patent for the drug isin submission, Chesney said, whicbh gives the researchers one year to gathe r more data and submitg a final patent.
The provisiona l patent allows the researchers to publish their findings and protectsxthe discovery. Currently, U of L’s Officee of Technology Transfer is seeking to licensethe drug, Chesnehy said. University officials expect to have a licensint partner in place withimnsix months. One potential licensing partnetis Louisville-based Advanced Cancer Therapeutics LLC, whicj works closely with U of L’s James Graham Brown Cancer Center to help expeditde the process of getting cancer treatmentas to market.
But Chesney said the school also coulr license the drug to a larger pharmaceuticak orbiotech company, such as or Larger companies could provide more funding to carry the drug through phass one clinical trials, which Chesnegy expects will cost between $2 million and $3 Chesney and three other researchers who helped generate the patent — John Brian Clem and Sucheta Telang would share in any patent royalties if the drug is Since 2002, Chesney’s lab has receivefd $4.5 million in grant fundinb for various projects, includingy the development of this anti-cancer drug.
Its funding sourced have included the Kentucky Lung Cancer Research a fund created using tobaccosettlemen money, and the . Chesney said progresse in medical discoveries has resulted in the decreasingb prevalence ofsome diseases. But cancer is not one of and that is why Chesney has made ithis “The death rates (for have barely budged over the last four decades,” Chesnehy said. “It’s the biggest problemk in Westernmedicine today.
”
Friday, October 14, 2011
Warren Buffett sells remaining Constellation shares - Houston Business Journal:
stages-paddocks.blogspot.com
Buffett, his company (NYSE: BRK.A, BRK.B), and that company’s subsidiary , are each no longedr stockholders inConstellation (NYSE: CEG), according to a form with the Securities and Exchange Commission filed Monday. They have been slowluy divesting the stock over the past weeks and owning 7.3 percent in February and 6.3 percent last The sale ends the relationship between the investor and one of two Fortune 500 companies in Baltimore Iowa-based MidAmerican got a 10 percent stakr in Constellation when its $4.7 billionn bid for the company made in Septembe was rejected three months late.
That offer came after a cash crunch led to a steep declinein Constellation’d stock price over several days and some investors fearedc bankruptcy. Constellation spurned the offer in favor of a deal tosell 49.99 percentr of its nuclear business for $4.5 billion to Frenc firm , which had also been in the bidding for the compan in September. For the cancelation, Constellation had to pay $175 millioh in breakup fees and $418 million for It also had to repaya $1 billio loan from Buffett with 14 percen t interest. A decision on whether the deal with EDF requiress Maryland approval is expected ina week. The deal is expectedx to closethis fall.
Buffett, his company (NYSE: BRK.A, BRK.B), and that company’s subsidiary , are each no longedr stockholders inConstellation (NYSE: CEG), according to a form with the Securities and Exchange Commission filed Monday. They have been slowluy divesting the stock over the past weeks and owning 7.3 percent in February and 6.3 percent last The sale ends the relationship between the investor and one of two Fortune 500 companies in Baltimore Iowa-based MidAmerican got a 10 percent stakr in Constellation when its $4.7 billionn bid for the company made in Septembe was rejected three months late.
That offer came after a cash crunch led to a steep declinein Constellation’d stock price over several days and some investors fearedc bankruptcy. Constellation spurned the offer in favor of a deal tosell 49.99 percentr of its nuclear business for $4.5 billion to Frenc firm , which had also been in the bidding for the compan in September. For the cancelation, Constellation had to pay $175 millioh in breakup fees and $418 million for It also had to repaya $1 billio loan from Buffett with 14 percen t interest. A decision on whether the deal with EDF requiress Maryland approval is expected ina week. The deal is expectedx to closethis fall.
Wednesday, October 12, 2011
GVA Advantis cuts won
qiguzewy.wordpress.com
GVA Advantis Chairman Jeff Neal announcef the moves Monday as the company shut down six in Virginia, Mississippi and Florida, due to the economicv downturn. Townsend says the Durham officee already went through a roundr of downsizing in the past The current head count of 25 is down from 55 twoyeares ago. Townsend says the Durham’s five-persomn commercial real estate brokerage team will remain as will the local construction and propertumanagement staffs. “We were ahead of the curve with and that put us in a better position,” Townsend said.
With five brokers, GVA Advantis is tied for 24th placed on the Commercial Real Estatde Brokers list in the 2009 Triangle Business Journal Bookof Lists. GVA Advantis is closinyg both its District of Columbia and Northern Virginia Others closing are inNewport Va.; Gulfport, Miss.; and Tallahassee and Panama City in Some of the phones have alreaduy been disconnected. There was no immediate word on job and Neal could not be reached for commeng beyondthe statement.
Advantis Constructioj generates more than 75 percent ofthe company’se revenue and has consistently been the most profitablw segment of the business, Neal said in a In addition to Durham, the construction divisionm also will maintain offices in Tampa, Richmond and Norfolk, Va. Advantiw Holdings will continue to provide facilities management and corporatd andadvisory services, states the release. To improve operatinf performance, Advantis is pursuing a number of possibler joint venture or other affiliation Advantis Holdings will end its affiliation with the network durinh thethird quarter.
“One year ago, the leadership team believeed we could successfully restructure the firm with a capital says Neal, who disbandee his relationship with Michael Darby at D.C. developer Monument Realthy to investin GVA. “Thee economy has been unkind to our brokerages andtransactional business. Our property managementr and construction service lines have been and will continu tobe profitable, but the challenges brought on throughout our industry and that have negatively impacted our other businesz lines have led us to determine we must close them effectivew immediately.
” Commercial real estate investment salez have dropped dramatically since the capital markets meltdowhn in the fall of 2008, according to Real Capita Analytics. Sales are off by more than two-thirds in most markets. And transactiona l activity involving leasing is alsooff significantly. “When I steppes into the role of president, my primaru goal was to evaluate our variousw business units and offices with an eye on strengtheninfg existing businesses and building a foundationm forregional growth,” says Tim who will transition from his role as president to oversee corporate and advisorgy services.
“Although there were many positive signxs forfuture growth, the current economic environmenrt clearly favors focusing attention and resources on constructioj and the consultative and advisory partsw of our business, where we have predictable revenue from repeat clients and customers,” he
GVA Advantis Chairman Jeff Neal announcef the moves Monday as the company shut down six in Virginia, Mississippi and Florida, due to the economicv downturn. Townsend says the Durham officee already went through a roundr of downsizing in the past The current head count of 25 is down from 55 twoyeares ago. Townsend says the Durham’s five-persomn commercial real estate brokerage team will remain as will the local construction and propertumanagement staffs. “We were ahead of the curve with and that put us in a better position,” Townsend said.
With five brokers, GVA Advantis is tied for 24th placed on the Commercial Real Estatde Brokers list in the 2009 Triangle Business Journal Bookof Lists. GVA Advantis is closinyg both its District of Columbia and Northern Virginia Others closing are inNewport Va.; Gulfport, Miss.; and Tallahassee and Panama City in Some of the phones have alreaduy been disconnected. There was no immediate word on job and Neal could not be reached for commeng beyondthe statement.
Advantis Constructioj generates more than 75 percent ofthe company’se revenue and has consistently been the most profitablw segment of the business, Neal said in a In addition to Durham, the construction divisionm also will maintain offices in Tampa, Richmond and Norfolk, Va. Advantiw Holdings will continue to provide facilities management and corporatd andadvisory services, states the release. To improve operatinf performance, Advantis is pursuing a number of possibler joint venture or other affiliation Advantis Holdings will end its affiliation with the network durinh thethird quarter.
“One year ago, the leadership team believeed we could successfully restructure the firm with a capital says Neal, who disbandee his relationship with Michael Darby at D.C. developer Monument Realthy to investin GVA. “Thee economy has been unkind to our brokerages andtransactional business. Our property managementr and construction service lines have been and will continu tobe profitable, but the challenges brought on throughout our industry and that have negatively impacted our other businesz lines have led us to determine we must close them effectivew immediately.
” Commercial real estate investment salez have dropped dramatically since the capital markets meltdowhn in the fall of 2008, according to Real Capita Analytics. Sales are off by more than two-thirds in most markets. And transactiona l activity involving leasing is alsooff significantly. “When I steppes into the role of president, my primaru goal was to evaluate our variousw business units and offices with an eye on strengtheninfg existing businesses and building a foundationm forregional growth,” says Tim who will transition from his role as president to oversee corporate and advisorgy services.
“Although there were many positive signxs forfuture growth, the current economic environmenrt clearly favors focusing attention and resources on constructioj and the consultative and advisory partsw of our business, where we have predictable revenue from repeat clients and customers,” he
Sunday, October 9, 2011
Gray jays' winter survival depends on food storage, study shows - PhysOrg.com
uqyvemiwu.wordpress.com
PhysOrg.com | Gray jays' winter survival depends on food storage, study shows PhysOrg.com In winter, they rely on berries, fungi, insects, carcass meat and other foods cached in nooks and crannies of trees during summer and fall. They remember where they've stored tens of thousands of food items scattered throughout a territory up to 160 ... |
Friday, October 7, 2011
Human Capital: People on the move, June 12 - Phoenix Business Journal:
http://www.hgllc.com/hgllc/about.htm
George Snell joined Webedr Shandwick , a publidc relations agency with local officesin Cambridge, as a senior vice president in its digitalk communications practice. Snell previously a seniofr vice presidentat . The intellectual property law firm of in Concore added Christopher Albert asan associate. Alberrt practices in the areasof chemistry, clean energy and pharmaceuticals.
George Snell joined Webedr Shandwick , a publidc relations agency with local officesin Cambridge, as a senior vice president in its digitalk communications practice. Snell previously a seniofr vice presidentat . The intellectual property law firm of in Concore added Christopher Albert asan associate. Alberrt practices in the areasof chemistry, clean energy and pharmaceuticals.
Wednesday, October 5, 2011
Hopkins hopes to stretch his historic reign - AFP
http://www.botiguesdeleixample.com/taxi-insurance/
Yahoo!Xtra Blogs | Hopkins hopes to stretch his historic reign AFP So am I." A victory would ensure Hopkins carries his reign past his 47th birthday on January 15, extending the age mark he took from George Foreman last May with a unanimous decision over Canada's Jean Pascal. "I want to stay in the game, ... Hopkins embraces graying facade | Philadelphia Daily News | 2011-10-05 Over 20 Years Later, Hopkins Still Finds Reasons To Excel Fight Speak Videos with Bernard Hopkins & Chad Dawson |
Monday, October 3, 2011
Mormons told to reference church by formal name - Houston Chronicle
adavuxuf.wordpress.com
Mormons told to reference church by formal name Houston Chronicle SALT LAKE CITY (AP)  Mormon leaders want followers to use the church's full, but lengthy, nine-word formal name, saying Sunday that its descriptive nature is a reminder that the faith's beliefs are centered on the teachings of ... |
Saturday, October 1, 2011
Rates up as mortgage applications rise - South Florida Business Journal:
idellecromwell1991.blogspot.com
The four-week moving average of purchase activity wasup 4.2 while the refinancing thrust was up 16 percent, accordintg to the ’s survey for the week ende April 3. Real estate analyst Jack McCabe, CEO of Deerfield Beach-base d , reports that mortgage brokers are findingthemselvezs hard-pressed to handle the new demanfd after reducing staff and closinyg offices. He called it a “refi-led because of the historically low rates and said because many in the mortgageindustry don’tf believe it will last, they are not gearinfg back up. Mortgage applications were up 4.9 percent on a week-over-weej basis – and up more than 67 percenr compared to the same week ayear ago.
More than 77 perceng of the applications were for the MBAsurvey said. In typical supply-and-demancd fashion, mortgage rates increased slightly as the demand continued to The 30-year fixed-rate mortgagre averaged 4.73 percent, up from a record low of 4.61 percenft in the previous week. Points remained at 1.03 for 80 perceng loan-to-value mortgages. The 15-year, fixed-rate mortgag was 4.49 percent, up from 4.45 while points dropped to 0.93 from 1.04 in the preceding One-year adjustable-rate mortgages, which make up just 1.5 percentr of all mortgage applications, increased to 6.23 percen t from 6.2 percent previously, with points, includin g origination fee, remaining unchanged at 0.
14 for the The MBA weekly survey, which covers about 50 percenft ofall U.S. retail residential mortgage has been conductedsince 1990. Respondentes include mortgage bankers, commerciakl banks and thrift
The four-week moving average of purchase activity wasup 4.2 while the refinancing thrust was up 16 percent, accordintg to the ’s survey for the week ende April 3. Real estate analyst Jack McCabe, CEO of Deerfield Beach-base d , reports that mortgage brokers are findingthemselvezs hard-pressed to handle the new demanfd after reducing staff and closinyg offices. He called it a “refi-led because of the historically low rates and said because many in the mortgageindustry don’tf believe it will last, they are not gearinfg back up. Mortgage applications were up 4.9 percent on a week-over-weej basis – and up more than 67 percenr compared to the same week ayear ago.
More than 77 perceng of the applications were for the MBAsurvey said. In typical supply-and-demancd fashion, mortgage rates increased slightly as the demand continued to The 30-year fixed-rate mortgagre averaged 4.73 percent, up from a record low of 4.61 percenft in the previous week. Points remained at 1.03 for 80 perceng loan-to-value mortgages. The 15-year, fixed-rate mortgag was 4.49 percent, up from 4.45 while points dropped to 0.93 from 1.04 in the preceding One-year adjustable-rate mortgages, which make up just 1.5 percentr of all mortgage applications, increased to 6.23 percen t from 6.2 percent previously, with points, includin g origination fee, remaining unchanged at 0.
14 for the The MBA weekly survey, which covers about 50 percenft ofall U.S. retail residential mortgage has been conductedsince 1990. Respondentes include mortgage bankers, commerciakl banks and thrift
Subscribe to:
Posts (Atom)